Strawberry 100% chronicles the school years of Junpei Manaka, a high school student and aspiring movie director, and his relationships with the girls that enter his life. At the start of the series, he encounters a mystery woman with strawberry-print panties, who he quickly becomes intrigued with. Hoping to find her, he finds the notebook of Aya Tojo nearby, who turns out to be an ordinary-looking girl. However, he soon discovers that Aya is a gifted writer, and the two become friends. Meanwhile, he believes the mystery girl to be Tsukasa Nishino, the most popular girl in his school. The two soon start a relationship together. However, he eventually realises Tsukasa is not the mystery woman he had been searching for, but chooses to continue their relationship. During his entrance exam for his desired high school, Izumimaka High, he discovers that Aya is in fact the mystery girl.